Connie Wu, PhD

Connie Wu

Research: I am a postdoctoral research fellow in the Cardiovascular Research Center and Anesthesia Center for Critical Care Research at Massachusetts General Hospital, and an affiliate of the Broad Institute of MIT and Harvard. I am using computational, genomic, and cellular tools to identify novel microRNAs targeting the mRNA of NPPA, the gene encoding atrial natriuretic peptide (ANP). I am leading efforts to develop microRNA inhibitors (anti-miRs) as therapeutics to raise ANP levels, which could provide a novel approach to treating patients with hypertension and heart failure.

Training: I earned a BA in Biochemistry and Molecular Biology from Boston University in 2008 and a PhD in Biochemistry from Tufts University Sackler School of Graduate Biomedical Sciences in 2012. My PhD research focused on investigating the role of hypoxia in the regulation of microRNAs in mammalian cells as related to the development of pulmonary arterial hypertension.